![](https://www.gurukpo.com/wp-content/uploads/2015/10/11.jpeg)
Differentiation
Mr. Mukesh Agnihotri Assistant Professor, Biyani Girls College explained about differentiation with example.
Faculty: IT 2019 Sample Papers with Solutions Sr. No. Paper Name Question Paper Link Solution Link 1. Cloud Computing Click Here Click Here 2. Analysis & Design of Algorithm Click Here …
Faculty: IT 2019 Sample Papers with Solutions Sr. No. Paper Name Question Paper Link Solution Link 1. Java Technologies Click Here Click Here 2. Web Technologies Click Here Click Here 3. …
Faculty: IT 2019 Sample Papers with Solutions Sr. No. Paper Name Question Paper Link Solution Link 1. Discrete Mathematics Click Here Click Here 2. Programming in C & C++ Click Here …
Faculty: Science 2019 Sample Papers with Solutions Sr. No. Paper Name Question Paper Link Solution Link 1 Immunology, Virology and Pathogenesis Click Here Click Here 2. Cell Biology Click Here Click …
Faculty: Science 2019 Sample Papers with Solutions Sr. No. Paper Name Question Paper Link Solution Link 1 Plant Biotechnology Click Here Click Here 2. Genetic Engineering Click Here Click Here
Mr. Mukesh Agnihotri Assistant Professor, Biyani Girls College explained about differentiation with example.
Mr. Mukesh Agnihotri Assistant Professor, Biyani Girls College explained about differentiation with example.
Dr. Varun Maru Assistant Professor, Biyani Girls College explained about Gullik and Fayol theory of public administration.
Dr. Varun Maru Assistant Professor, Biyani Girls College explained about Gullik and Fayol theory of public administration.
Ms. Shashi Naruka Assistant Professor, Biyani Girls College explained about HTML, formatting tags, HR rule, Standards of HTML.
Ms. Shashi Naruka Assistant Professor, Biyani Girls College explained about HTML, formatting tags, HR rule, Standards of HTML.
DEFINITION:- It is a collection of air in the pleural space normally the pressure in the pleural space is negetive compare to atmospheric presure. This negetive pressure is require to maintain …
DEFINITION:-
It is a collection of air in the pleural space normally the pressure in the pleural space is negetive compare to atmospheric presure. This negetive pressure is require to maintain lung inflation.
ETIOLOGY:-
It may be due to internal or external trauma which can be differentiate according to the type of trauma & site of involve it.
TYPES:-
1. Closed pneumothorax:-
There is no association with external injury or wound this is most common form of sponteneous pneumothorax.
Cause:-
A. Injury to the lungs due tio any mechanical ventilation
B. Injury to the lungs due to any broken ribs
C. Rupture of the bells & belbs
D. Perforation
E. Under weight smokers
2. Open pneumothorax:-
In this type of pneumothorax air enter into pleural space due to external injury or trauma. for eg:- stab wound , gun shoot , any surgical procedure of thorax
3. Tension pneumothorax:-
Pneumothorax with rapid accumulation of air into pleural space causinghigh intrapleural pressure with result in tension of heart & blood vessel.
Clinical features :-
1. Lungs may collapse
2. Mediastinal shift
4.Hemothorax-
Accumulation of bloos in intrapleural space . it is mostly associated with open pneumothorax.
Causes:-
1. Cheast trauma
2. Lung malignancy
3. Comlication of anticoagulant therapy
4. Pulmonary embolism
5. Tearing of pleural adhesions
5.Cyclothorax:
If pneumothorax is mild tachycardia &dyspnea will occur . if it is severe in condition respiratory distress, severe dyspnea, rapid breathing &air hunger which isa severe form of respiratory distress , chest pain , cough with or without haemoptysis , anxiety
DIAGNOSTIC EVALUATION:-
1. Physical examination on auscultation no breath sounds over the affected area
2. Cheast x rays shows the pressure & shadow of pneumothorax
3. Examination of purcussion shows hyper ressonance.
Medical management :-
1. It depends on cause or severity of the diseasecondition in mild cases constructive treatment ilke oxygen administration should be provided
2. In severe cases cheast drainage should be done small chest trube is inserted into the second intercostal space , in caes of severe accumulation the tube is inserted into 4th intercostal space to remove the accumulated air .
SURGICAL MANAGEMENT:-
1. In case of repeated pneumothorax pleuroctomy may be done
2. Pleurodysis:-
Artificial production of adhesions between visceral 7 parietal pleura with the help of chemical agent.
3. Needle venting :-
Pricking a large bore needle into the thorax to remove accumulated air
NURSING MANAGEMENT :-
1. PROVIDE SUPPLIMENT OXYGEN PLACE THE PATIENT IN SEMIFOWLERS POSITION.
2. OBTAIN TRAY FOR DRAIN OUT THE ACCUMULATED SUBSTANCES
3. AFTER DRAINAGE ASK THE PATIENT TO REPORT ANY INCREASE DYSPNEA
4. PALOPATED FOR SUBCUTENEOUS EMPHYSEMA IN UPPER CHEAST & NECK REGION.
Description:-It is a syndrome condition which is characterized by decrease tissue perfusion &impaired cellular perfusion.. This results in imbalance in supply &demand of oxygen supply. When a cell experiences a state …
Description:-It is a syndrome condition which is characterized by decrease tissue perfusion &impaired cellular perfusion..
This results in imbalance in supply &demand of oxygen supply.
When a cell experiences a state of hypo perfusion, the demand for oxygen & nutrient exceeds the supply
Classification:-for the purpose of discussion, shock can be classified:-
1. Hypovolemic shock
2. Cardiogenic shock
3. Septic shock
4. Anaphylactic shock
5. Neurogenic shock
• Hypovolemic shock:-it is hypo perfusion condition of tissues due to decrease amount of body fluid from normal level
Many causes affect the volume of body fluid-hemorrhage, vomiting, diarrhea, excessive dieresis, burns..
• Cardiogenic shock:-cardiogenic shock caused by the dysfunctioning of the cardiac muscles which cause altered contraction of cardiac muscles.
Ultimately results decrease pumping capacity of heart…
• Neuregenic shock:-it is a haemodynamic phenomenon that can occurs within 30 minutes of a spinal cord injury at the 5th thoracic vertebra or above &last up to 6th weeks..
• Anaphylactic shock:-it is acute &life threatening condition in which hypersensitivity reaction to a sensitizing substances like drugs, vaccines, chemicals etc.
• Septic shock:-it is a systemic inflammatory response to a documented or suspected infection..
Pathophysiology:-hypovolemia due to any cause-decrease circulatory volume-decrease venous return-decrease stroke volume-decrease cardiac output-decrease cellular oxygen supply-decrease tissue perfusion…
Sign & symptoms:-
i. Decrease urine output
ii. Increase temperature
iii. Tachypnoea
iv. Cyanosis
v. Pallor skin
vi. Cool & calmy skin
vii. Decrease bowel sounds
viii. Vomiting
ix. Cramping
x. Alteration in mental status
xi. Swelling of lips
xii. Shortness of breath
xiii. Wheezing
xiv. Decrease cerebral perfusion
xv. Confusion
xvi. Edema of larynx
• Diagnosis:-
• History taking
• Physical examination
• E.c.g.
• Chest x-ray
• Continues pulse oxymetry
• Laboratory tests.
Management:-
Fluid therapy:-except for cardiogenic & neurogenic shock,all other classification of shock involve decrease circulating blood volume so for recovery fluid therapy is required.
Key words:-
Hypo perfusion
Tachypnoea
Sepsis
Hypersensitivity
Impaired
Hypovolemia…
Defination- Major histocompatibility complex is tightly linked clusterof genes whose product play role in intercellular recognition and to make defference between self and nonself molecule.MHC molecule act as a antigen presenting …
Defination- Major histocompatibility complex is tightly linked clusterof genes whose product play role in intercellular recognition and to make defference between self and nonself molecule.MHC molecule act as a antigen presenting structure. T cell recognize antigen only when it is combined with an MHC molecule.
Types- MHC molecule have two types
1) Class I MHC molecule 2) Class II MHC molecule
Structure- Type I MHC- It has a 45 KD alpha chain associated noncovalently with a 12 KD beta 2 microglobulin molecule. Alpha chain is a trans membraneglycoprotein encoded by A, B, C region in human HLA complexes and by K, D/L region in mice. Association of alpha chain and beta 2 microglobulin require for expression of class I molecule on cell membrane. Alpha chain bind to plasma membrane by its hydrophobic transmembrane segment and hydrophilic cytoplasmic tail. Alpha chain is made up of three external domain(α1,α2,α3). Each domain have 90 amino acid, a trans membrane domain have 25 hydrophobic amino acid, a short segment of hydrophilic amino acid and a cytoplasmic segment of 30 amino acid. Peptide which bind to class I MHC is made up of 8-9 amino acid.
Type II MHC- Class II MHC bind to peptide and present these peptides to CD4 T celles. These peptides derived from exogenous protein. Peptide degred with in the endocytic processing pathway Class II MHC peptide contain 13-18 amino acid. Peptide binding cleft in class II MHC molecule is open at both ends and allow peptide to extend at both ends like a long hot dog in a buns.Peptide have an internal sequence containing 7-10 amino acid. This sequence has an aromatic or hydrophobic residue at the amino terminus and 3 additional hydrophobic residue in the middle portion and carboxy terminal end of the peptide.
Many people set goals, work out their priorities, then fail with the last critical step; to plan HOW they will use their time. Time is like any other resource; but for …
Many people set goals, work out their priorities, then fail with the last critical step; to plan HOW they will use their time. Time is like any other resource; but for some reason the attitude towards the importance of time planning is often considered to be less important than the planning associated with the use of equipment, machines, money and people.
Effectiveness means accomplishing goals and achieving results. Planning is normally accepted as a means of implementing major task and complex projects. It is universally agreed that careful planning normally saves time and other resources. For careful planning we need to consider following strategy
• It is important to recognize the importance of thinking and the contribution it makes to the process of planning
• To decide how we spend our time working on the tasks that help us achieve the result we wish for
Every day we all have to make decisions about the use of our time. It is essential this decision making process is continually linked to the results we want to achieve. Ask almost anyone if they would like to speak another language, travel more or develop a greater sense of well being, happiness or self esteem; they will probably answer “Yes” to some or all of these goals. When you then ask them “so when are you starting the lessons; the plans to travel more or taking some time to enjoy life more- tonight? Tomorrow? Over the weekend? The response probably would be, “No but I will soon”. This could be called long term planning. Obviously many people find it difficult to translate long term goals into actions that start here and now. The major reasons are a well ingrained diary or “Time Planning” habit that bears little relationship to their future goals, either in their personal or professional lives.
Imagine you all have to do is on the horizon. This horizon contains your goals, tasks, ideas and activities. Along the road you need to find the space for all these things in your diary. Imagine your diary as the road leading to your goals and you r present position as your daily plans. You are in control of the detail plan of the day and at the same time you can have a clear view of the time booked during the week and the month ahead. You can even glimpse the year in the far distance.
DEFINITION:- It is the collection of fluid in the pleural space. It is a type of primary disorder and due to this secondary sign and symptoms will occur. TYPES:- 1. Transudate …
DEFINITION:- It is the collection of fluid in the pleural space. It is a type of primary disorder and due to this secondary sign and symptoms will occur.
TYPES:-
1. Transudate ( Hydrothorax)
2. Exudate
1. Transudate:-
In this type fluid passess through the membranes.
2. Exudate:-
It is a leakage of fluid from the blood vessels into the tissues.
TRANSUDATE occurs in non inflammatory condition. It is a process of accumulation of proteins poor, cell poor fluid which move across intact capilliaries walls. For eg.;- increased hydrostatic pressure in the congestive heart fauilure, decrease onchotic pressure in renal and liver disease.
Accumulation of fluids and cells in an area of inflammation for eg;- Any inflammatory condition , pulmonary malignancies, nephrotic syndrome occurs due to exudate condition.
PATHOPHYSIOLOGY:-
TRANSUDATE:-
Any alteration in the formation and reabsorbation of pleural; fluid due to imbalance in hydrostatic and onchotic pressure . It has low content of protein & the nature of fluid is clear & pale yellow./
EXUDATE:-
It occurs due to any inflammation and bacterial infection, tumors which causes exudation process . It has a high protein content & fluid is dark yellow & amber.
Pleural effusion
CLINICAL FEATURES:-
1. Pleuritic pain
2. Progressive dyspnea
3.Decreased cheast wall movement
4. fever
5. chills
6. Malignant effusion may result in dyspnea and coughing
7. Malaise
DIAGNOSTIC EVALUATIONS:-
1. Physical Examination
2. Pleural biopsy
3. Chest X-ray
4. Pleural fluid analysis
5. C T scan
6. Thoracentesis
MEDICAL MANAGEMENT:-
1. To discusss he underlying cause to prevent reaccumulation of fluid to relief discomfort &dyspnea are the purpose of management including thoracentessis aspiration through syringe.
2. Provide appropriate antibiotics
3. Provide diuretics therapy
NURSING MANAGEMENT:-
1. Take care of patient and prepare him for thoracentesis procedure
2. Reduce the pain by maintain the position &administering analgesics
3. Educate the patient & his family regarding care of drain tube if the client is an out patient.
4. Frequent turning of the patient position will facilitate drainage of the accumulation fluid.
Description:- Basal Cell Carcinoma Definition:- Basal cell carcinoma is a type of skin Cancer; Basal cell carcinoma often appears as a Waxy bump, though it can take other form. Basal cell …
Description:- Basal Cell Carcinoma
Definition:- Basal cell carcinoma is a type of skin Cancer; Basal cell carcinoma often appears as a Waxy bump, though it can take other form. Basal cell carcinoma occurs most often on areas of the skin that are often exposed to the sun, such as own face and neck.
Causes:- (1). Basal cell carcinoma occurs when one of the skin’s basal cell develops a mutation in its DNA, a Mutation in the DNA causes a Basal Cell to multiply rapidly and continue growing when it would normally die. Eventually the accumulating abnormal cell may form a Cancerous tumor
(2). Ultraviolet light & other causes; Much of the damage to DNA in basal cells is thought to result from ultraviolet(UV) radiation found in sunlight and in commercial tanning beds.But sun exposure doesn’t explain skin cancers that develop on skin not ordinarily exposed to sunlight. This indicates that other other factors may contribute to own risk of skin cancer , such as being exposed to toxic substances or having a condition that weakens own immune system
Symptoms:- Although a general warning sign of skin cancer is a sore that won’t heal or that repeatedly bleeds and scabs over, basal cell cancer may also appear as:-
1) A pearly white or waxy bump,
2) Often with visible blood vessels, on face , ears or neck.
3) A flat, scaly, brown or flesh-colored patch on back or chest.
4) More rarely, a white, waxy scar
Remedies:-
1). Eat at least 5 servings of fruits and vegetables each day, especially those food rich in the Antioxidants Beta Carotene, vitamin C , and citrus fruits.
2). Include in Diet plenty of whole grains, sea vegetables, beans and soyabeans, hot peppers, cabbage, tomatoes, onions, rosemary, garlic grapes, licorice root, green tea, white fish, mushrooms.
3). Avoid red Meat, processed foods, red and yellow dyes, monosodium glutamate, nitrites(found in cured meats), saccharin sugar, dairy products, alcohol, caffeine containing drinks.
Definition-:Diabetes melietus is a metabolic disorder which is characterized by hyperglycemic condition due to defective functioning of insulin hormone… It may be due to abnormal secretion of insulin & altered functioning …
Definition-:Diabetes melietus is a metabolic disorder which is characterized by hyperglycemic condition due to defective functioning of insulin hormone…
It may be due to abnormal secretion of insulin & altered functioning of insulin hormone which secrets by beta cells of pancreas…
Etiology-: according to etiology it divides in 3 types;
• Insulin dependent diabetes melietus
• Non insulin dependent diabetes melietus
• Gestational induced diabetes melietus….
Absolute or relative lack of insulin produce by beta cells resulting in hyper glycemia….
Impaired secretory respons of insulin to rises in glucose & due to this gluneogenesis may occurs..
IDDM:-it may cause due to following reasons-
• Autoimmunity
• Viral infections
• Environmental theories
• Other disease conditions.
• Old age
NIDDM:-It may cause by following reasons-
• Hereditary
• Genetic
• Obesity
• Beta cells defect
GIDM:-It define as glucose intolerance occurring during pregnancy &disappear after delivery…
Clinical menifestations:-there are many sign & symptoms :
1. Hyperglycemia
2. Weight loss
3. Poly urea
4. Poly depsia
5. Poly phagia
6. Blurred vision
7. Altered tissue perfusion
8. Poor wound healing
9. Recurrent infection
10. Skin infection may be appear
11. Dry skin
12. Kitoacidosis
13. Dehydration
Diagnostic evaluations:-many tests are useful for evaluation
• Glucose tolerance test
• Fasting glucose test
• Blood test
• Urine test
• Physical examinations
• History taking
Management;-management of this divided in 3 types;-
1. Medical management
2. Dietary management
3. Exercise
• Medical management: many hypoglycemic agents are given for reduce level of glucose:-
Eg; tolbutamide; metformine; glycazideetc;
• Dietary management;-dietary control with caloric restriction of carbohydrate maintain ideal body weight .
The goal of meal planning is to control blood glucose level& weight reduction is another goal;;
• Exercise:-regular schedule of exercise also helpful in reduction of blood glucose level
Complications:-
1. Diabetes keto acidosis
2. Cerebral vascular disease
3. Retinopathy
4. Neuropathy
5. Peripheral vascular disease
6. Cardiac disorders